Analysis of the Effectiveness of Gingival Crevicular Blood in Estimating Diabetes
DOI:
https://doi.org/10.70409/rmhhut.v19i1.148Keywords:
complications of diabetes, diabetes mellitus, blood glucose, gingival crevicular bloodAbstract
Diabetes is a public health problem in Peru. An intraoral blood sampling method would facilitate screening by dentists, regardless of whether or not a diagnosis has been made. Objective: To determine if gingival crevicular blood sampling has a comparable level of effectiveness to capillary blood sampling in estimating glycemic status. Method: Observational, descriptive, cross-sectional study. The sample consisted of 58 participants diagnosed with gingivitis or periodontitis who presented with bleeding on probing in at least one site. Periodontal parameters, including probing depth and gingival index, were evaluated using the Williams graduated periodontal probe. Gingival crevicular blood (GCB) and capillary blood samples were obtained by fingerstick for glucose level determination using a glucometer. Results: Pearson's correlation coefficient showed a very high correlation between SCG and SPC, with a coefficient of 0.982 and a statistical significance value of p < 0.001, indicating a strong and statistically significant positive association between the two measurements. Conclusion: SCG may be a potential screening tool for diabetes during periodontal examination, especially in patients with unknown history of the disease and moderate bleeding on probing.
References
Cloete L. Diabetes mellitus: an overview of the types, symptoms, complications and management. Nurs Stand [Internet]. 2022 Jan 5 [Citado 06 feb 2026];37(1):61-66. Disponible en: 10.7748/ns.2021.e11709
Trujillo-Minaya F, Vera-Ponce VJ, Torres-Malca JR, Zuzunaga-Montoya FE, Guerra-Valencia J, De-La-Cruz-Vargas JA., Cruz-Ausejo L. (2023). Factores asociados al cribado de Diabetes Mellitus en población Peruana ¿problema para la salud pública?. Rev Cuid [Internet]. 2023 Apr [Citado 06 feb 2026]; 14( 1 ): e17. Disponible en: https://doi.org/10.15649/cuidarte.2792
Antar SA, Ashour NA, Sharaky M, Khattab M, Ashour NA, Zaid RT, et al. Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments. Biomed Pharmacother [Internet]. 2023 Dec [Citado 06 feb 2026];168:115734. Disponible en: 10.1016/j.biopha.2023.115734
Hossain MJ, Al-Mamun M, Islam MR. Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused. Health Sci Rep [Internet]. 2024 Mar 22 [Citado 06 feb 2026];7(3):e2004. Disponible en: 10.1002/hsr2.2004
Fakheran O, Bencze B, Mischak I, Vegh D, Payer M. The reliability of using gingival crevicular blood to measure blood glucose and hba1c levels in the dental setting: a systematic review and meta-analysis. Clin Oral Investig [Internet]. 2024 May 4 [Citado 06 feb 2026];28(5):299. Disponible en: 10.1007/s00784-024-05685-4
Nibali L, Gkranias N, Mainas G, Di Pino A. Periodontitis and implant complications in diabetes. Periodontol 2000 [Internet]. 2022 Oct [Citado 06 feb 2026];90(1):88-105. Disponible en: 10.1111/prd.12451
Shinjo T, Nishimura F. The bidirectional association between diabetes and periodontitis, from basic to clinical. Jpn Dent Sci Rev [Internet]. 2024 Dec [Citado 06 feb 2026];60:15-21. Disponible en: 10.1016/j.jdsr.2023.12.002
Ramakrishnan H, Nandini VV, Ayyadurai MM, Ramalingam S, Amanullah A. A Clinical Study to Assess the Severity of Periodontal Disease in Relation to Glycemic Status of Type II Diabetic Individuals. J Pharm Bioallied Sci [Internet]. 2022 Jul [Citado 06 feb 2026];14(Suppl 1):S356-S359. Disponible en: 10.4103/jpbs.jpbs_73_22
Tomic D, Shaw JE, Magliano DJ. The burden and risks of emerging complications of diabetes mellitus. Nat Rev Endocrinol [Internet]. 2022 Sep [Citado 06 feb 2026];18(9):525-539. Disponible en: 10.1038/s41574-022-00690-7
Zhang X, Zhou X, Han X, Fu Z, Wang L, Li Y, et al. The Morbidity and Comorbidity of Nonalcoholic Fatty Liver Disease and Different Glucose Intolerance Strata in a Community-Based Chinese Population. Metab Syndr Relat Disord [Internet]. 2020 Aug [Citado 06 feb 2026];18(6):284-290. Disponible en: 10.1089/met.2019.0107
Ansari Moghadam S, Abbaszade H, Sartipi M, Ansari Moghadam A. Evaluating the association between gingival crevicular blood glucose levels and finger capillary blood glucose levels according to periodontal status. Eur J Med Res [Internet]. 2024 Jan 30 [Citado 06 feb 2026];29(1):86. Disponible en: 10.1186/s40001-023-01611-8
Rapone B, Ferrara E, Santacroce L, Topi S, Converti I, Gnoni A, Scarano A, Scacco S. Gingival Crevicular Blood as a Potential Screening Tool: A Cross Sectional Comparative Study. Int J Environ Res Public Health [Internet]. 2020 Oct 9 [Citado 06 feb 2026];17(20):7356. Disponible en: 10.3390/ijerph17207356
Dash KC, Ramanna PK, Varghese LJ, Reddy U, Nambiar S, Patel A, Mishra D. Estimation of Gingival Crevicular Blood as Noninvasive Method to Determine the Blood Glucose Level: A Comparative Study. J Contemp Dent Pract. 2023 Jun 1 [Citado 06 feb 2026];24(6):381-384. Disponible en: 10.5005/jp-journals-10024-3473
Patel C, Dave B, Patel R, Kumar S, Dattani V, Joshi S, Haque M. Gingival Crevicular Blood Glucose as a Novel Method for Screening Diabetes Mellitus in Periodontally Compromised Patients. Cureus [Internet]. 2023 May 24 [Citado 06 feb 2026];15(5):e39444. Disponible en: 10.7759/cureus.39444
Parihar S, Tripathi R, Parihar AV, Samadi FM, Chandra A, Bhavsar N. Estimation of gingival crevicular blood glucose level for the screening of diabetes mellitus: A simple yet reliable method. J Oral Biol Craniofac Res [Internet]. 2016 Sep-Dec [Citado 06 feb 2026];6(3):198-203. Disponible en: 10.1016/j.jobcr.2016.05.004
Downloads
Published
How to Cite
Conference Proceedings Volume
Section
License
Copyright (c) 2026 Britto Ebert Falcón-Guerrero
This work is licensed under a Creative Commons Attribution 4.0 International License.
